Flexible EFP
But wait, do I need to recompute fragment parameters for each new geometry of my polymer? Not necessary, if you did a homework. Check out this paper on Flexible EFP.
The original code developed by Dr. Yongbin Kim can be found here.
Check out our tutorial showing how to setup QM/EFP calculations for a protein system using Flexible EFP procedure! QM/EFP calculations using BioEFP and FlexEFP