.. _bioefp:

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BioEFP
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BioEFP is a scheme to split a macromolecule into fragments.
Proteins can be split along C-Ca bonds, as shown below.

.. image:: ../images/BioEFP.jpg
   :width: 200

The model is described `here <https://pubs.acs.org/doi/abs/10.1021/acs.jpcb.6b04166>`_.
The original work used the following script `step2.gen.gamess.pl` **Where is it?**.
For a new robust version of the script check out this
`BioEFP tutorial <https://github.itap.purdue.edu/Slipchenko-group/>`_ **The tutorial is not there yet!**